Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184146 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| SCHEMBL9699705 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL28090977 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| SCHEMBL27991767 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL29271905 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| SCHEMBL27524278 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBKMT2ATDP1 | |
| SCHEMBL27898396 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| SCHEMBL3073042 | 0.77 | PLAU (0.39) | ALDH1A1MAPTPOLBHSD17B10TSHR | |
| SCHEMBL4684077 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBHSD17B10KMT2A | |
| SCHEMBL10667678 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1221339-A | Use of inhibitors of cellular Na+/H+ exchanger (NHE) for preparing medicament for normalizing serum lipids | HOECHST AG (DE) | 1999-06-30 | — | — | CN | claimed |
| CN-1209995-A | Use of sodium-hydrogen exchanger inhibitors for the production of a medicament for reducing the adverse effects of substances on the heart | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-03-10 | — | — | CN | claimed |
| CN-1195508-C | Use of sodium-hydrogen exchanger inhibitors for the production of a medicament for reducing the adverse effects of substances on the heart | AVENTIS PHARMA GMBH (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1221339-A | Use of inhibitors of cellular Na+/H+ exchanger (NHE) for preparing medicament for normalizing serum lipids | HOECHST AG (DE) | 1999-06-30 | — | — | CN | disclosed |
| CN-1209995-A | Use of sodium-hydrogen exchanger inhibitors for the production of a medicament for reducing the adverse effects of substances on the heart | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-03-10 | — | — | CN | disclosed |