SCHEMBL27504381

SCHEMBL27504381

COC(C[SiH3])C(OC)(OC)OCC1CO1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28727329 0.79 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL14832617 0.77 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL6813404 0.72
SCHEMBL4337268 0.69 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1
SCHEMBL17515094 0.68
SCHEMBL230767 0.67 TSHR (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL28091716 0.67 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL7218169 0.67 TSHR (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL6367903 0.66 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL28763333 0.65 ALDH1A1 (0.61) ALDH1A1TSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104249579-B Ink jet recording method 富士胶片株式会社 2018-06-12 CN disclosed
CN-104249579-A Ink jet recording method FUJIFILM CORP 2014-12-31 CN disclosed
CN-1243063-C Alkyleneimine/organic barrier coatings with bis-silane additives DOW CORNING (US) 2006-02-22 CN disclosed
CN-1408016-A Alkylenimine/organic carrier coatings having bis-silane additives DOW CORNING (US) 2003-04-02 CN disclosed