Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25119732 | 0.84 | KMT2A (0.43) | KMT2AKCNN4ALDH1A1KIF11KCNA5 | |
| SCHEMBL27678470 | 0.79 | KMT2A (0.42) | KMT2AKCNN4KIF11MDM4MDM2 | |
| SCHEMBL9537104 | 0.79 | KCNN4 (0.44) | KMT2AKCNN4ALDH1A1KIF11KCNA5 | |
| SCHEMBL5799829 | 0.75 | KMT2A (0.43) | KMT2AKCNN4ALDH1A1KIF11KCNA5 | |
| SCHEMBL29045223 | 0.75 | KMT2A (0.43) | KMT2AKCNN4ALDH1A1KIF11KCNA5 | |
| SCHEMBL27453562 | 0.73 | KMT2A (0.44) | KMT2AKCNN4ALDH1A1KIF11POLB | |
| SCHEMBL11278048 | 0.73 | KMT2A (0.48) | KMT2AKCNN4ALDH1A1KIF11MDM4 | |
| SCHEMBL1235122 | 0.73 | KMT2A (0.48) | KMT2AKCNN4ALDH1A1KIF11MDM4 | |
| SCHEMBL1028846 | 0.72 | KMT2A (0.44) | KMT2AKCNN4ALDH1A1KIF11MDM4 | |
| SCHEMBL1545921 | 0.71 | KMT2A (0.56) | KMT2AALDH1A1KCNA5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209744-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | CN | disclosed |