Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 10/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508043 | 0.79 | KMT2A (0.45) | KCNN4ALDH1A1KIF11KCNA5POLB | |
| SCHEMBL1277655 | 0.74 | KIF11 (0.58) | KIF11 | |
| SCHEMBL1144412 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KCNA5POLBKMT2ACYP1A2 | |
| SCHEMBL167043 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KCNA5POLBKMT2ACYP1A2 | |
| SCHEMBL476790 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KCNA5POLBKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL1277652 | 0.73 | KIF11 (0.56) | KIF11 | |
| Hydrochloric Acid SCHEMBL1277658 | 0.73 | KIF11 (0.56) | KIF11 | |
| Hydrochloric Acid SCHEMBL2203097 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KCNA5POLBKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL476789 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KCNA5POLBKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6373800 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KCNA5POLBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535192-A1 | NOVEL DNA GYRASE INHIBITORS, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME. | HOFFMANN LA ROCHE (CH) | 1993-04-07 | — | — | EP | disclosed |