Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542210 | 0.89 | BRD4 (0.46) | BRD4PAX8F2RL3CREBBPMEN1 | |
| SCHEMBL24449497 | 0.87 | BRD4 (0.49) | BRD4PAX8SIGMAR1 | |
| SCHEMBL18055477 | 0.87 | BRD4 (0.49) | BRD4PAX8F2RL3CREBBPMEN1 | |
| SCHEMBL14907964 | 0.86 | BRD4 (0.48) | BRD4PAX8F2RL3CREBBPMEN1 | |
| SCHEMBL15656810 | 0.83 | ACHE (0.52) | BRD4PAX8F2RL3CREBBPSLC7A5 | |
| SCHEMBL14907966 | 0.82 | BRD4 (0.46) | BRD4PAX8F2RL3CREBBP | |
| SCHEMBL3297083 | 0.82 | BRD4 (0.46) | BRD4PAX8F2RL3CREBBPMEN1 | |
| SCHEMBL15725251 | 0.82 | BRD4 (0.46) | BRD4PAX8F2RL3CREBBPRAB9A | |
| SCHEMBL25377809 | 0.81 | BRD4 (0.47) | BRD4PAX8MEN1RAB9AKMT2A | |
| SCHEMBL27450194 | 0.81 | BRD4 (0.51) | BRD4PAX8F2RL3CREBBPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149191-C | Azetidine derivatives, Preparation and medicines containing them | ���ĵ�˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1316991-A | Azetidine derivatives, preparation and medicines containing them | AVENTIS PHARMA SA (FR) | 2001-10-10 | — | — | CN | disclosed |