Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976377 | 0.78 | ALOX15 (0.37) | EPHX1EP300HIF1ACREBBPALOX15 | |
| SCHEMBL27519971 | 0.78 | ALOX15 (0.37) | EPHX1EP300HIF1ACREBBPALOX15 | |
| SCHEMBL28976380 | 0.78 | ALOX15 (0.37) | EPHX1EP300HIF1ACREBBPALOX15 | |
| SCHEMBL7389756 | 0.76 | EP300 (0.33) | EP300HIF1ACREBBPALOX15 | |
| SCHEMBL7390216 | 0.76 | EP300 (0.33) | EP300HIF1ACREBBPALOX15 | |
| Hydrochloric Acid SCHEMBL29069900 | 0.76 | MAPK1 (0.36) | EPHX1EP300HIF1ACREBBPALOX15 | |
| SCHEMBL1355956 | 0.73 | EP300 (0.31) | EP300HIF1ACREBBPALOX15 | |
| SCHEMBL27470790 | 0.72 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL7387498 | 0.71 | EP300 (0.30) | EP300HIF1ACREBBP | |
| SCHEMBL27469789 | 0.71 | ALOX15 (0.33) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344245-A | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | WARNER LAMBER CO (US) | 2002-04-10 | — | — | CN | claimed |
| CN-1170811-C | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | ��ʲ | 2004-10-13 | — | — | CN | disclosed |
| CN-1344245-A | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | WARNER LAMBER CO (US) | 2002-04-10 | — | — | CN | disclosed |