Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472661 | 0.86 | HTR1F (0.58) | HTR1FKMT2AALDH1A1MEN1PKM | |
| SCHEMBL5211088 | 0.86 | HTR1F (0.58) | HTR1FSMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL5209076 | 0.86 | HTR1F (0.58) | HTR1FGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL5210102 | 0.86 | HTR1F (0.58) | HTR1FGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL27457322 | 0.86 | HTR1F (0.58) | HTR1FGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL5212244 | 0.86 | HTR1F (0.58) | HTR1FGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL5209513 | 0.85 | HTR1F (0.65) | HTR1FSMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL5212194 | 0.85 | HTR1F (0.57) | HTR1FGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL5209959 | 0.85 | HTR1F (0.62) | HTR1FSMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL27472240 | 0.82 | HTR1F (0.61) | HTR1FGAAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149195-C | 5-HTIF agonists | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1340045-A | 5-HTIF agonists | LILLY CO ELI (US) | 2002-03-13 | — | — | CN | disclosed |