Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27424975 | 0.91 | TSHR (0.70) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL13816768 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL27424971 | 0.85 | HSD17B10 (0.62) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL28379040 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL110117 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL2925689 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL5808886 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL3360968 | 0.82 | TSHR (0.81) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL23294932 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL28237362 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168720-C | Aryl alkanoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1305465-A | Aryl alkanoylpyridazines | MERCK PATENT GMBH (DE) | 2001-07-25 | — | — | CN | disclosed |