Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425427 | 0.83 | ALDH1A1 (0.43) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL27455049 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1HIF1ACA2CA5A | |
| SCHEMBL11597420 | 0.81 | TDP1 (0.50) | ALDH1A1TDP1CYP3A4HIF1ACA2 | |
| SCHEMBL10748239 | 0.80 | HSD17B10 (0.55) | ALDH1A1TDP1LMNAHSD17B10PDE7A | |
| SCHEMBL30279963 | 0.79 | PTPRC (0.46) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL532452 | 0.79 | PTPRC (0.46) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL13043154 | 0.79 | POLB (0.53) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL27601633 | 0.78 | ALDH1A1 (0.49) | PTPRCS100A4ALDH1A1TDP1HIF1A | |
| SCHEMBL2860338 | 0.77 | TSHR (0.49) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL135919 | 0.77 | CA1 (0.45) | PTPRCS100A4ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101337895-B | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH NEW TECHNOLOGY DEV CT | 2011-05-11 | — | — | CN | claimed |
| CN-101337895-A | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-101337892-A | Method for preparing 2-brom-5-nitrobenzotrifluoride | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-106316864-A | Preparation method of 4-methyl-3-trifluoromethyl phenylamine | 苏州天马精细化学品股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-101337895-B | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH NEW TECHNOLOGY DEV CT | 2011-05-11 | — | — | CN | disclosed |
| CN-101337895-A | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-101337892-A | Method for preparing 2-brom-5-nitrobenzotrifluoride | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-100427483-C | Anthranilic acid amide derivatives and their pharmaceutical use | NOVARTIS AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101198607-A | Phenylacetamides suitable as protein kinase inhibitors | NOVARTIS AG (CH) | 2008-06-11 | — | — | CN | disclosed |
| CN-101045727-A | Inhibitors of tyrosine kinases | NOVARTIS AG (CH) | 2007-10-03 | — | — | CN | disclosed |
| CN-1324022-C | Tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2007-07-04 | — | — | CN | disclosed |
| CN-1279026-C | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2006-10-11 | — | — | CN | disclosed |
| CN-1720244-A | Anthranilic acid amide derivatives and their pharmaceutical use | NOVARTIS AG (CH) | 2006-01-11 | — | — | CN | disclosed |
| CN-1675195-A | Tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2005-09-28 | — | — | CN | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1342149-A | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |