Butanone

Butanone

SCHEMBL27509357

CC(O)N(C)C.CCC(C)=O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
TRPA1 O75762 1/20 0.38
FFAR3 O14843 1/20 0.33
TSHR P16473 1/20 0.33
CHRNB2 P17787 3/20 0.32
CHRNB4 P30926 3/20 0.32
CHRNA4 P43681 3/20 0.32
TP53 P04637 1/20 0.32
GRIN2D O15399 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
OPRM1 P35372 2/20 0.32
CACNA1F O60840 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP2B6 P20813 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL357729 0.83 FFAR3 (0.56) ALDH1A1TDP1FFAR3TSHRTP53
Butanone SCHEMBL457538 0.82
Butanone SCHEMBL17201869 0.79 ALDH1A1 (0.67) ALDH1A1TDP1TRPA1FFAR3TSHR
Acetic Acid SCHEMBL358311 0.79 FFAR3 (0.47) ALDH1A1TDP1FFAR3TSHRTP53
Butanone SCHEMBL2458814 0.79 ALDH1A1 (0.67) ALDH1A1TDP1TRPA1FFAR3TSHR
Butanone SCHEMBL19681448 0.79 ALDH1A1 (0.67) ALDH1A1TDP1TRPA1FFAR3TSHR
Butanone SCHEMBL3901207 0.77 ALDH1A1 (0.48) ALDH1A1TDP1TSHR
Butanone SCHEMBL28158094 0.77 ALDH1A1 (0.62) ALDH1A1TDP1TRPA1FFAR3TSHR
Butanone SCHEMBL1576889 0.77 TDP1 (0.62) ALDH1A1TDP1TRPA1FFAR3TSHR
Bicarbonate SCHEMBL1131466 0.76 TP53 (0.47) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1218000-C Pigment dispersion resin for cathode electrophoresis paint and its pigment paste JIANGSU HONGYE COATING SCI & T (CN) 2005-09-07 CN disclosed
CN-1493627-A Pigment dispersion resin for cathode electrophoresis paint and its pigment paste 江苏鸿业涂料科技产业有限公司 2004-05-05 CN disclosed