Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.42 |
| ▸ | CCKAR | P32238 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533179 | 0.82 | CCKBR (0.40) | CCKBRCCKARCYP2C9CYP2C19 | |
| SCHEMBL27528202 | 0.79 | CCKBR (0.42) | CCKBRCCKARCYP2C9CYP2C19GABRA1 | |
| SCHEMBL4424638 | 0.79 | CCKBR (0.44) | CCKBRCCKARCYP2C9CYP2C19 | |
| SCHEMBL27510203 | 0.77 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL4413353 | 0.76 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL27510490 | 0.76 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL4413355 | 0.73 | CYP2C9 (0.39) | CCKBRCCKARCYP2C9CYP2C19GABRA1 | |
| SCHEMBL11961451 | 0.71 | BRD4 (0.68) | CCKBR | |
| SCHEMBL27528231 | 0.71 | CCKBR (0.42) | CCKBRCCKARCYP2C9CYP2C19GABRA1 | |
| SCHEMBL27587107 | 0.70 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242007-A | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds | ELAND PHARMACEUTICAL CORP (US) | 2000-01-19 | — | — | CN | disclosed |