Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.63 |
| ▸ | CTSL | P07711 | 6/20 | 0.63 |
| ▸ | CTSB | P07858 | 5/20 | 0.63 |
| ▸ | CTSS | P25774 | 4/20 | 0.63 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160782 | 1.00 | CTSK (0.63) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL7181854 | 0.87 | CTSK (0.70) | CTSKCTSLCTSBCTSS | |
| SCHEMBL27473690 | 0.85 | CTSK (0.60) | CTSKCTSLCTSBCTSS | |
| SCHEMBL608854 | 0.84 | CTSK (0.72) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL3383041 | 0.84 | CTSK (0.72) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL6943810 | 0.84 | CTSK (0.72) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL7167532 | 0.84 | CNR2 (0.47) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL11302585 | 0.83 | CTSK (0.62) | CTSKCTSLCTSBCTSS | |
| SCHEMBL17596884 | 0.81 | CTSK (0.55) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL160926 | 0.81 | CTSK (0.55) | CTSKCTSLCTSBCTSSPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1341590-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341593-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341592-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1207095-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-02-03 | — | — | CN | disclosed |