Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTPRA | P18433 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320686 | 0.75 | HDAC8 (0.33) | CYP2D6KDM4EPTPRA | |
| SCHEMBL18115388 | 0.75 | LMNA (0.44) | CYP2D6KDM4EPTPRA | |
| SCHEMBL4479123 | 0.73 | SLC6A2 (0.45) | CYP2D6KDM4E | |
| SCHEMBL6284707 | 0.72 | TSHR (0.39) | CYP2D6KDM4E | |
| SCHEMBL6323436 | 0.72 | TSHR (0.39) | CYP2D6KDM4E | |
| SCHEMBL12479150 | 0.71 | ADORA2A (0.37) | CYP2D6KDM4E | |
| SCHEMBL8876690 | 0.70 | — | — | |
| SCHEMBL6287348 | 0.70 | HIF1A (0.44) | CYP2D6KDM4E | |
| SCHEMBL6284708 | 0.70 | TSHR (0.46) | CYP2D6KDM4E | |
| SCHEMBL28659666 | 0.70 | PTPRA (0.39) | KDM4EPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235870-C | Novel use of phenyl hetero alkylamine derivatives | ASTRAZENECA AB (SE) | 2006-01-11 | — | — | CN | disclosed |
| CN-1411435-A | Novel use of phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2003-04-16 | — | — | CN | disclosed |