Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15219273 | 0.72 | KDM4C (0.38) | KDM4CHDAC1HDAC6 | |
| SCHEMBL23416935 | 0.69 | KDM4C (0.38) | KDM4CHDAC1HDAC6 | |
| SCHEMBL11916028 | 0.68 | KDM4C (0.35) | KDM4CHDAC1HDAC6 | |
| SCHEMBL11919035 | 0.68 | IDO1 (0.36) | KDM4CHDAC1HDAC6 | |
| SCHEMBL442421 | 0.67 | KDM4C (0.46) | KDM4CHDAC1HDAC6 | |
| SCHEMBL27836778 | 0.66 | HDAC1 (0.32) | HDAC1HDAC6 | |
| SCHEMBL27577388 | 0.66 | — | — | |
| SCHEMBL27832416 | 0.66 | TYR (0.31) | — | |
| SCHEMBL2804255 | 0.64 | KDM4C (0.40) | KDM4CHDAC1HDAC6 | |
| SCHEMBL28745225 | 0.64 | GRM5 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252070-A | 5,7-disubstituted 4-aminopyrido [2,3,-d] pyrimidine compounds and their use as adenosine kinase inhibitors | ABBOTT LAB (US) | 2000-05-03 | — | — | CN | disclosed |