Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596664 | 0.77 | IDO1 (0.57) | IDO1ALDH1A1MAOBTAAR1AOC3 | |
| SCHEMBL155804 | 0.76 | IDO1 (0.61) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL2714973 | 0.75 | IDO1 (0.67) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL31065556 | 0.75 | IDO1 (0.67) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL12874173 | 0.72 | IDO1 (0.57) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL13590064 | 0.71 | IDO1 (0.61) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL13594319 | 0.71 | IDO1 (0.61) | IDO1MCL1ALDH1A1MAOBTAAR1 | |
| SCHEMBL514213 | 0.71 | TAAR1 (0.48) | IDO1ALDH1A1TAAR1NPC1L3MBTL1 | |
| SCHEMBL1520141 | 0.71 | IDO1 (1.00) | IDO1ALDH1A1MAOBTAAR1 | |
| SCHEMBL514224 | 0.71 | IDO1 (0.61) | IDO1MCL1ALDH1A1MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190437-C | pteridine compound for treating psoriasis | ASTRAZENECA AB (SE) | 2005-02-23 | — | — | CN | disclosed |
| CN-1404482-A | Pteridine compounds for the treatment of psoriasis | ASTRAZENECA AB (SE) | 2003-03-19 | — | — | CN | disclosed |