SCHEMBL275152

SCHEMBL275152

COc1cc(O)ccc1C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.64
CYP3A4 P08684 2/20 0.50
MAPT P10636 1/20 0.50
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
ACHE P22303 1/20 0.45
APP P05067 1/20 0.44
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
TUBB1 Q9H4B7 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CAPN1 P07384 1/20 0.42
PARP1 P09874 1/20 0.42
MAOA P21397 1/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RET P07949 1/20 0.42
KIF5B P33176 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427137 1.00 MAOB (0.64) MAOBCYP3A4MAPTESR1ESR2
Hydrazine SCHEMBL10758378 0.96 MAOB (0.59) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL23861426 0.83 MAOB (0.48) MAOBCYP3A4ESR1ESR2ACHE
SCHEMBL263095 0.81 MAOB (0.58) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL31703288 0.81 MAOB (0.58) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL30514387 0.80 MAOB (0.70) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL119396 0.80 MAOB (0.70) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL16542012 0.80 ALDH1A1 (0.49) MAOBCYP3A4MAPTESR1ESR2
SCHEMBL16542009 0.80 MAOB (0.43) MAOBESR1ESR2TUBB1CTSL
SCHEMBL16542013 0.80 TUBB1 (0.57) MAOBCYP3A4MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350185-A Biphenyl hydroxamic derivative and preparation method and application thereof 聊城大学 2025-01-24 CN claimed
CN-114181047-A Method for preparing biphenol from cresol 中国科学院大连化学物理研究所 2022-03-15 CN claimed
CN-107089898-B Method for synthesizing cyclohexanol compounds by catalytic hydrogenation of biomass phenolic compounds 浙江工业大学 2020-06-23 CN claimed
CN-107089898-A A kind of method of biomass phenolic compound catalytic hydrogenation synthesizing cyclohexane 1 alcohols compound 浙江工业大学 2017-08-25 CN claimed
US-4968759-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-11-06 US claimed
WO-2025217099-A1 INHIBITORS FOR HYDROGEN EMBRITTLEMENT AND METHODS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-10-16 WO disclosed
WO-2025217091-A1 ODORANTS FOR FLUIDS, ODORIZED FLUIDS, METHODS, AND SYSTEMS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-10-16 WO disclosed
EP-3947365-B1 SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF BIONOMICS LTD (AU) 2025-10-01 EP disclosed
CN-119350185-A Biphenyl hydroxamic derivative and preparation method and application thereof 聊城大学 2025-01-24 CN disclosed
US-12162871-B2 Inhibitors of VAP-1 ACUCELA INC. (US) 2024-12-10 US disclosed
US-12139473-B2 Substituted-N-heteroaryl compounds and uses thereof BIONOMICS LIMITED (AU) 2024-11-12 US disclosed
EP-4217062-B1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-10-09 EP disclosed
EP-1675814-A1 PHENOXYETHER DERIVATIVES AS PPAR MODULATORS ELI LILLY AND COMPANY (US) 2006-07-05 EP disclosed
US-20050201265-A1 Phthalocyanine compound, process for producing the same, and optical recording medium containing the same MITSUI CHEMICALS, INC. (JP) 2005-09-15 US disclosed
WO-2005037763-A1 PHENOXYETHER DERIVATIVES AS PPAR MODULATORS ELI LILLY AND COMPANY (US) 2005-04-28 WO disclosed
EP-1482013-A1 PHTHALOCYANINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME MITSUI CHEMICALS, INC. (JP) 2004-12-01 EP disclosed
US-5102962-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-04-07 US disclosed
US-4897438-A BLEND WITH A PHENOLIC RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-01-30 US disclosed
US-4772742-A POLYESTER INTERMEDIATES AMOCO CORPORATION (US) 1988-09-20 US disclosed
US-4709080-A POLYESTERS STANDARD OIL COMPANY (US) 1987-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139473-B2 Substituted-N-heteroaryl compounds and uses thereof SCN3A, KCND3, GRIN3A MAOB 2112/4885CYP3A4 2075/4885MAPT 379/4885
US-12162871-B2 Inhibitors of VAP-1 VAPB, VAPA, TOE1 MAOB 1440/4885CYP3A4 4363/4885MAPT 2213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.