Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184878 | 0.83 | KDM4E (0.67) | SMN1; SMN2LMNAMAPTKDM4EHTT | |
| SCHEMBL16585159 | 0.83 | KDM4E (0.67) | SMN1; SMN2LMNAMAPTKDM4EHTT | |
| SCHEMBL2184876 | 0.83 | KDM4E (0.67) | SMN1; SMN2LMNAMAPTKDM4EHTT | |
| SCHEMBL8133474 | 0.81 | MAPT (0.47) | SMN1; SMN2LMNAMAPTKDM4ENPC1 | |
| Acrylic Acid Methyl Ester SCHEMBL30663418 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTKDM4EHTT | |
| SCHEMBL3225999 | 0.77 | MAPT (0.78) | SMN1; SMN2LMNAMAPTKDM4ENPC1 | |
| SCHEMBL3092733 | 0.77 | MAPT (0.58) | SMN1; SMN2LMNAMAPTKDM4EHTT | |
| SCHEMBL294835 | 0.77 | TSHR (0.46) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL5745570 | 0.75 | MAPT (0.65) | SMN1; SMN2LMNAMAPTKDM4ENPC1 | |
| SCHEMBL5745572 | 0.75 | MAPT (0.65) | SMN1; SMN2LMNAMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1185154-A | Bicyclic amines as insecticides | ZENECA LTD (GB) | 1998-06-17 | — | — | CN | disclosed |