Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | JUN | P05412 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585159 | 1.00 | KDM4E (0.67) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL2184876 | 1.00 | KDM4E (0.67) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL27470412 | 0.89 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL27470413 | 0.89 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL21001847 | 0.86 | RAB9A (0.71) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL27515328 | 0.83 | SMN1; SMN2 (0.56) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL5852187 | 0.83 | RAB9A (0.61) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL13957158 | 0.83 | RAB9A (0.61) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL30012000 | 0.83 | RAB9A (0.61) | KDM4EMAPTRAB9ANPC1JUN | |
| SCHEMBL30930826 | 0.83 | RAB9A (0.61) | KDM4EMAPTRAB9ANPC1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110462473-A | Adhesive layer-attached single-sided protective polarizing film, image display device, and continuous production method therefor | NITTO DENKO CORP | 2019-11-15 | — | — | CN | disclosed |
| CN-110383120-A | Polarizing coating and image display device with adhesive phase | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110382648-A | Adhesive layer, single-sided protective polarizing film with adhesive layer, image display device, and continuous production method therefor | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110383121-A | Unilateral protection polarizing coating, image display device and its method for continuous production with adhesive phase | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| US-10364256-B2 | Biaryl pyrazoles as NRF2 regulators | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-30 | — | — | US | disclosed |
| CN-109790433-A | Adhesive composition, adhesive phase, the polarizing coating with adhesive phase, liquid crystal display panel and image display device | 日东电工株式会社 | 2019-05-21 | — | — | CN | disclosed |
| US-20180282349-A1 | BIARYL PYRAZOLES AS NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-10-04 | — | — | US | disclosed |
| CN-108463750-A | Unilateral protection polarizing coating, image display device and its method for continuous production with adhesive phase | 日东电工株式会社 | 2018-08-28 | — | — | CN | disclosed |
| US-9994558-B2 | Multicyclic compounds and methods of using same | Karyopharm Therapeutics Inc. (US) | 2018-06-12 | — | — | US | disclosed |
| WO-2017060854-A1 | BIARYL PYRAZOLES AS NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |
| US-6313153-B1 | ADMINISTERING PYRIDYLACRYLAMIDE COMPOUND FOR THERAPY OF NEPHRITIS | TSUMURA & CO. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1000935-A1 | PYRIDYLACRYLAMIDE DERIVATIVES AND NEPHRITIS REMEDIES AND TGF-$g(b) INHIBITORS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5428168-A | Substituted butyrolactol ether derivative | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| EP-0527817-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| WO-1991017157-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364256-B2 | Biaryl pyrazoles as NRF2 regulators | NFE2L2, KEAP1, NQO1 | KDM4E 2962/4885MAPT 2730/4885RAB9A 2634/4885 |
| US-20180282349-A1 | BIARYL PYRAZOLES AS NRF2 REGULATORS | NFE2L2, KEAP1, NQO1 | KDM4E 2962/4885MAPT 2730/4885RAB9A 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.