Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6066165 | 0.97 | KMT2A (0.39) | KMT2AALDH1A1MEN1TDP1AXL | |
| Phosphine SCHEMBL6066159 | 0.97 | KMT2A (0.39) | KMT2AALDH1A1MEN1TDP1AXL | |
| Hydrazine SCHEMBL5282146 | 0.95 | KMT2A (0.37) | KMT2AALDH1A1MEN1TDP1AXL | |
| SCHEMBL16019052 | 0.84 | MEN1 (0.33) | KMT2AALDH1A1MEN1TDP1NFE2L2 | |
| SCHEMBL13946887 | 0.84 | ALDH1A1 (0.34) | KMT2AALDH1A1MEN1TDP1NFE2L2 | |
| SCHEMBL678617 | 0.84 | EGFR (0.36) | KMT2AALDH1A1MEN1TDP1NFE2L2 | |
| SCHEMBL6066125 | 0.83 | MEN1 (0.38) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL8582433 | 0.79 | MEN1 (0.30) | KMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL6718662 | 0.79 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1NFE2L2MAPT | |
| SCHEMBL1094509 | 0.79 | PDPK1 (0.34) | KMT2AALDH1A1MEN1TDP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 953 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431491-A | Synthesis method of Fmoc-Xaa-Ser (Psi (Me, me) Pro) -OH pseudo dipeptide | 杭州湃肽生化科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118440010-A | Preparation method of 4, 6-dichloro-5-pyrimidine acetaldehyde | 诚达药业股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-117110483-A | Liquid chromatographic analysis and detection method for 5-pyrimidine formaldehyde compounds | 常州合全药业有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-106311176-A | Particle adsorption agent for indole adsorption and preparation method thereof | 北京益净环保设备科技有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106311178-A | Functional plate for indole adsorption and preparation method thereof | 北京益净环保设备科技有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106268698-A | Feature board for Adsorption of Pyridine and preparation method thereof | 北京益净环保设备科技有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-106268697-A | Granule adsorbent for Adsorption of Pyridine and preparation method thereof | 北京益净环保设备科技有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-105622613-A | Method for synthesizing ibrutinib | AOPUTON (SHANGHAI) MEDICAL TECH CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-103058935-B | Pyrimidine compound as well as preparation method and use for same | UNIV SICHUAN | 2015-05-06 | — | — | CN | claimed |
| CN-102180880-B | Method for synthesizing bromophenyl pyrazolo[3,4-d]pyrimidine derivative | UNIV CHANGZHOU | 2014-04-09 | — | — | CN | claimed |
| CN-103058935-A | Pyrimidine compound as well as preparation method and use for same | UNIV SICHUAN | 2013-04-24 | — | — | CN | claimed |
| CN-102115475-B | Method for synthesizing pyrazolo[3,4-d]pyrimidine derivative by two steps | UNIV CHANGZHOU | 2013-01-16 | — | — | CN | claimed |
| EP-0506628-B1 | Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances | SIGMA TAU IND FARMACEUTI (IT) | 1996-09-18 | — | — | EP | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
| EP-4747260-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| US-20260132133-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC (US) | 2026-05-14 | — | — | US | disclosed |
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |
| US-4003633-A | Color display device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132133-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KRAS, HRAS, BCL6 | KMT2A 4453/4885ALDH1A1 3584/4885MEN1 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.