Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.40 |
| ▸ | REN | P00797 | 8/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532955 | 0.86 | SSTR4 (0.38) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL7310959 | 0.77 | SSTR4 (0.42) | SSTR4RENCTSC | |
| SCHEMBL3364696 | 0.75 | SSTR4 (0.41) | SSTR4RENCTSC | |
| SCHEMBL2688364 | 0.75 | SSTR4 (0.41) | SSTR4RENCTSC | |
| SCHEMBL1194327 | 0.75 | SSTR4 (0.41) | SSTR4RENCTSC | |
| SCHEMBL23230712 | 0.75 | SSTR4 (0.44) | SSTR4RENCTSC | |
| SCHEMBL294851 | 0.75 | SSTR4 (0.41) | SSTR4RENCTSC | |
| SCHEMBL295081 | 0.75 | SSTR4 (0.44) | SSTR4RENCTSC | |
| SCHEMBL25338599 | 0.75 | REN (0.41) | SSTR4REN | |
| SCHEMBL3849670 | 0.74 | SSTR4 (0.43) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |