Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972584 | 0.95 | PPARD (0.50) | PPARDL3MBTL1MAPTNPSR1LTB4R | |
| SCHEMBL74512 | 0.86 | PPARD (0.54) | PPARDL3MBTL1MAPTNPSR1LTB4R | |
| SCHEMBL8404955 | 0.85 | L3MBTL1 (0.72) | PPARDL3MBTL1MAPTNPSR1NISCH | |
| SCHEMBL31360878 | 0.85 | L3MBTL1 (0.72) | PPARDL3MBTL1MAPTNPSR1NISCH | |
| SCHEMBL7999552 | 0.85 | PPARD (0.60) | PPARDL3MBTL1MAPTNPSR1LTB4R | |
| SCHEMBL23881819 | 0.84 | L3MBTL1 (0.47) | PPARDL3MBTL1MAPTNPSR1KDM4E | |
| SCHEMBL23881855 | 0.84 | L3MBTL1 (0.47) | PPARDL3MBTL1MAPTNPSR1HTR1A | |
| SCHEMBL28813037 | 0.84 | L3MBTL1 (0.47) | PPARDL3MBTL1MAPTNPSR1HTR1A | |
| SCHEMBL29474947 | 0.84 | L3MBTL1 (0.47) | PPARDL3MBTL1MAPTNPSR1KDM4E | |
| SCHEMBL11407644 | 0.84 | L3MBTL1 (0.47) | PPARDL3MBTL1MAPTNPSR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1263751-C | Novel compounds | ASTRAZENECA AB (SE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1541214-A | Novel compounds | — | 2004-10-27 | — | — | CN | disclosed |