Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237835 | 0.91 | PDE1C (0.65) | ADRA1ACACNA1BADRA2AADRA2BADRA2C | |
| SCHEMBL27544297 | 0.90 | ADORA3 (0.53) | CACNA1BADORA3CACNA1CCACNA1FCACNA1D | |
| SCHEMBL27516090 | 0.89 | ADORA3 (0.47) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL7236173 | 0.88 | CACNA1B (0.66) | ADRA1ACACNA1BADRA2AADRA2BADRA2C | |
| SCHEMBL27541954 | 0.87 | ADORA3 (0.46) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL27566516 | 0.87 | ABCC1 (0.56) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL28742845 | 0.86 | KDM4E (0.56) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL27517411 | 0.85 | ADORA3 (0.59) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL5854523 | 0.85 | CACNA1B (0.80) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F | |
| SCHEMBL5854519 | 0.85 | CACNA1B (0.80) | ADRA1ACACNA1BADORA3CACNA1CCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1261348-A | Dihydropyridine derivatives | AJINOMTO CO INC (JP) | 2000-07-26 | — | — | CN | disclosed |