Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576677 | 0.78 | HPRT1 (0.50) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7103569 | 0.77 | HPRT1 (0.48) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8903323 | 0.76 | HPRT1 (0.52) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL27976174 | 0.75 | HPRT1 (0.47) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL27463276 | 0.75 | HPRT1 (0.47) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8902756 | 0.70 | GPR3 (0.35) | HPRT1ALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL28857916 | 0.70 | HPRT1 (0.58) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL87109 | 0.69 | DNMT1 (0.42) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8359592 | 0.68 | HPGD (0.51) | ALDH1A1CYP1A2CYP2C19CYP2C9HPGD | |
| SCHEMBL1461844 | 0.68 | HPRT1 (0.50) | HPRT1ALDH1A1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235968-A | Substituted tricyclics | LILLY CO ELI (US) | 1999-11-24 | — | — | CN | disclosed |