Acetone

Acetone

SCHEMBL27517751

CC(C)=O.NNC(=O)NN

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
NFKB1 P19838 2/20 0.44
TSHR P16473 2/20 0.44
THPO P40225 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
CTSD P07339 1/20 0.36
KDM4E B2RXH2 2/20 0.35
CA2 P00918 1/20 0.35
PTGS1 P23219 1/20 0.35
MMP12 P39900 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HIF1A Q16665 1/20 0.35
CRBN Q96SW2 1/20 0.35
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20178517 0.88 NFKB1 (0.54) LMNANFKB1TSHRTHPOCYP1A2
SCHEMBL10623380 0.88 NFKB1 (0.54) LMNANFKB1TSHRTHPOCYP1A2
SCHEMBL64716 0.88
SCHEMBL8017494 0.84
SCHEMBL1537923 0.84
Potassium SCHEMBL18585217 0.84
Hydrochloric Acid SCHEMBL6335251 0.84
Water SCHEMBL7464138 0.84
Hydrochloric Acid SCHEMBL4489744 0.84
SCHEMBL8014825 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106032380-A Industrial production method of midazolam 王志训 2016-10-19 CN claimed
CN-106966844-B Graphene-based carbohydrazide metal complex crystal energetic material and preparation method thereof 西北工业大学 2018-11-20 CN disclosed
CN-106966844-A Graphene-based carbohydrazide metal complex crystal energetic material and preparation method thereof 西北工业大学 2017-07-21 CN disclosed
CN-106032380-A Industrial production method of midazolam 王志训 2016-10-19 CN disclosed
CN-1232395-A Pharmaceutical compounds containing polyamines substituted with electron affinity groups UNIV FLORIDA STATE (US) 1999-10-20 CN disclosed