SCHEMBL27518924

SCHEMBL27518924

O=S(=O)(O)C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
CYP2C19 P33261 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
MCOLN3 Q8TDD5 1/20 0.63
PTGS2 P35354 4/20 0.44
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
DAO P14920 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.39
AKT1 P31749 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B2 P19099 1/20 0.38
MTNR1A P48039 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28272795 0.82 ALDH1A1 (0.59) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL11537577 0.79 ALDH1A1 (0.61) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL7372442 0.79 ALDH1A1 (0.61) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL28849958 0.79 ALDH1A1 (0.61) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL5910599 0.77 ALDH1A1 (0.44) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL153450 0.77 ALDH1A1 (0.44) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL8915867 0.77 ALDH1A1 (1.00) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL8815065 0.76 AKR1C1 (0.53) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
SCHEMBL1432808 0.76 ALDH1A1 (0.42) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL18492474 0.76 ALDH1A1 (0.42) ALDH1A1CYP2C19L3MBTL1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101600822-B Multifilament, monofilament, adhesive-bonded fabric or band CIBA HOLDING INC. (CH) 2016-05-25 CN disclosed
CN-105585828-A LCP (liquid crystal polyester) composition KINGFA SCIENCE & TECHNOLOGY CO 2016-05-18 CN disclosed
CN-102007111-B Stabilization and surface modification of organic materials BASF SE 2014-06-25 CN disclosed
CN-101970559-B Additive mixture for styrene polymers BASF SE 2014-03-05 CN disclosed
CN-101848865-B Heat shielding additives BASF SE 2014-01-22 CN disclosed
CN-102964864-B Multifunctional furanone fluorescent whitening agent and preparation method thereof UNIV SOUTH CHINA NORMAL 2013-12-25 CN disclosed
CN-103443178-A Polycarbonate composition with improved impact strength SABIC INNOVATIVE PLASTICS IP 2013-12-11 CN disclosed
CN-103261301-A Improved electroless plating performance of laser direct structuring materials SABIC INNOVATIVE PLASTICS IP 2013-08-21 CN disclosed
CN-103249572-A Laser direct structuring material with all color properties SABIC INNOVATIVE PLASTICS IP 2013-08-14 CN disclosed
CN-101802068-B Silane coupling agents for filled rubbers BASF SE 2013-06-19 CN disclosed
CN-1336945-A Synthetic polymers comprising additive blends with enhanced effect CIBA SC HOLDING AG (CH) 2002-02-20 CN disclosed
CN-1334287-A Low thickness transparent polymeric articles CIBA SC HOLDING AG (CH) 2002-02-06 CN disclosed
CN-1274358-A Process for preparing phosphorus organic compounds CLARIANT FINANCE BVI LTD (VG) 2000-11-22 CN disclosed
CN-1257863-A Sterically hindered amine compound CIBA SC HOLDING AG (CH) 2000-06-28 CN disclosed
CN-1257492-A Block oligomers containing 1-hydrocarbyloxy-2, 2,6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials CIBA SC HOLDING AG (CH) 2000-06-21 CN disclosed
CN-1257493-A Block oligomers containing 1-hydrocarbyloxy-2, 2,6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials CIBA SC HOLDING AG (CH) 2000-06-21 CN disclosed
CN-1257495-A Block oligomers containing 1-hydrocarbyloxy-2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials CIBA SC HOLDING AG (CH) 2000-06-21 CN disclosed
CN-1188497-A Curable compositions CIBA GEIGY AG (CH) 1998-07-22 CN disclosed
CN-1165138-A Block oligomers containing 2, 2, 6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials CIBA GEIGY AG (CH) 1997-11-19 CN disclosed
CN-1032462-A The stabilizing agent of photochrome recording materials CIBA GEIGY AG (CH) 1989-04-19 CN disclosed