Phenol

Phenol

SCHEMBL27520174

Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
TSHR P16473 2/20 0.53
ALOX15 P16050 1/20 0.53
GAA P10253 2/20 0.50
THRB P10828 1/20 0.50
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.48
ALOX5 P09917 2/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
GPR35 Q9HC97 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP19A1 P11511 1/20 0.43
KDM4E B2RXH2 1/20 0.43
GFER P55789 1/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27815806 0.90 TSHR (0.63) ALDH1A1TSHRALOX15GAATHRB
Phenol SCHEMBL28180162 0.88 ALDH1A1 (0.61) ALDH1A1TSHRALOX15GAATHRB
3-Nitroaniline SCHEMBL28104603 0.86 ALDH1A1 (0.76) ALDH1A1TSHRALOX15GAATHRB
4-Nitroaniline SCHEMBL28750534 0.83 ALDH1A1 (0.69) ALDH1A1TSHRALOX15GAATHRB
Dinitrophenylene SCHEMBL27485738 0.82 ALDH1A1 (0.77) ALDH1A1TSHRALOX15LMNACES2
SCHEMBL65293 0.82 CYP19A1 (0.62) ALDH1A1TSHRALOX15MAPTSMN1; SMN2
Phenol SCHEMBL28273506 0.81 ALDH1A1 (0.53) ALDH1A1TSHRALOX15MAPTSMN1; SMN2
Phenol SCHEMBL28300096 0.81 TSHR (0.61) ALDH1A1TSHRALOX15MAPTSMN1; SMN2
Dinitrophenylene SCHEMBL28179781 0.81 ALDH1A1 (0.74) ALDH1A1TSHRALOX15LMNACES2
SCHEMBL1718796 0.80 ALDH1A1 (0.50) ALDH1A1TSHRALOX15GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103002952-B Hair conditioning composition comprising a cationic surfactant system, a direct dye and a nonionic thickener 宝洁公司 2017-02-15 CN disclosed
CN-103582680-B Disulfide dyes BASF SE (DE) 2016-04-06 CN disclosed
CN-103582680-A Disulfide dyes BASF SE 2014-02-12 CN disclosed
CN-1232509-C Diaminopyrazole derivatives and dyes containing these compounds P & G KRYROER CO (US) 2005-12-21 CN disclosed
CN-1441786-A Novel diamino pyrazole derivatives and dyes containing said compounds WELLA AG (DE) 2003-09-10 CN disclosed