Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778020 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL35574 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1260225 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25281286 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25275191 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25270629 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25275202 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25228041 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL20503422 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8999977 | 0.93 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167982-A | The manufacturing method of block copolymer and block copolymer | 电化株式会社 | 2019-08-23 | — | — | CN | disclosed |
| CN-103709076-B | A kind of method of continuous production biuret polyisocyanate | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2015-09-16 | — | — | CN | disclosed |
| CN-102770596-B | Agent for treating polyurethane elastic fiber, and polyurethane elastic fiber | MATSUMOTO YUSHI SEIYAKU KK | 2015-02-11 | — | — | CN | disclosed |
| CN-103709076-A | Method for continuously preparing biuret polyisocyanate | WANHUA CHEMICAL GROUP CO LTD | 2014-04-09 | — | — | CN | disclosed |
| CN-102770596-A | Agent for treating polyurethane elastic fiber, and polyurethane elastic fiber | MATSUMOTO YUSHI SEIYAKU KK | 2012-11-07 | — | — | CN | disclosed |
| CN-101072805-B | Method for producing colourless polyisocyanates that contain biuret groups and are stable in storage | BASF AG | 2011-05-11 | — | — | CN | disclosed |
| CN-101072805-A | Method for producing colourless polyisocyanates that contain biuret groups and are stable in storage | BASF AG (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1300263-C | Non-aqueous dispersion based antifouling paint composition | HEMPELS SKIBSFARVE FAB J C (DK) | 2007-02-14 | — | — | CN | disclosed |
| CN-1227304-C | Self-polishing marine antifouling paint compsn. comprising silicon-contaiing co-polymers and fibres | J C HEMPE S SKIBSFARVE FABRIK (DK) | 2005-11-16 | — | — | CN | disclosed |
| CN-1615346-A | Non-aqueous dispersion based antifouling paint composition | HEMPELS SKIBSFARVE FAB J C (DK) | 2005-05-11 | — | — | CN | disclosed |
| CN-1370205-A | Self-polishing marine antifouling paint compsn. comprising silicon-contaiing co-polymers and fibres | J C HEMPE S SKIBSFARVE FABRIK (DK) | 2002-09-18 | — | — | CN | disclosed |