Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184053 | 0.84 | ESR2 (0.52) | ESR2ALDH1A1KDM4ECYP19A1GABRG2 | |
| SCHEMBL820505 | 0.83 | ESR2 (0.48) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL2753256 | 0.80 | ESR2 (0.43) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL30359283 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL769515 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL2749473 | 0.78 | KDM4E (0.40) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| Methane SCHEMBL28932814 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL11132592 | 0.77 | ESR2 (0.43) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL30513178 | 0.77 | ESR2 (0.52) | SMN1; SMN2HIF1AESR2ALDH1A1KDM4E | |
| SCHEMBL2752011 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2HIF1AESR2ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541764-B | Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods | BASF SE | 2012-10-10 | — | — | CN | disclosed |
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| CN-101541762-A | Pyridazin-4-ylmethyl-sulfonamide compounds as fungicides and against arthropods | BASF SE (DE) | 2009-09-23 | — | — | CN | disclosed |
| CN-101541764-A | Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods | BASF SE (DE) | 2009-09-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | TPMT, NISCH, PPA1 | SMN1; SMN2 768/4885HIF1A 4066/4885ESR2 4708/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | SMN1; SMN2 824/4885HIF1A 4716/4885ESR2 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.