Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 11/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL741656 | 0.99 | SMYD3 (0.44) | SMYD3HRH4HRH3F7F3 | |
| SCHEMBL743889 | 0.82 | HRH4 (0.46) | SMYD3HRH4HRH3F7F3 | |
| SCHEMBL739788 | 0.80 | SMYD3 (0.51) | SMYD3HRH4HRH3F7F3 | |
| SCHEMBL27547475 | 0.79 | KMT2A (0.58) | SMYD3HRH4HRH3PYGLFLT3 | |
| Hydrochloric Acid SCHEMBL741745 | 0.79 | SMYD3 (0.50) | SMYD3HRH4HRH3F7F3 | |
| Trifluoroacetic Acid SCHEMBL1853964 | 0.79 | F10 (0.41) | SMYD3HRH4HRH3F7F3 | |
| Hydrochloric Acid SCHEMBL742545 | 0.78 | KMT2A (0.57) | SMYD3HRH4HRH3PYGLFLT3 | |
| SCHEMBL741757 | 0.77 | SMYD3 (0.46) | SMYD3PYGL | |
| SCHEMBL740522 | 0.77 | SMYD3 (0.48) | SMYD3HRH4HRH3F7F3 | |
| SCHEMBL741540 | 0.77 | KMT2A (0.45) | SMYD3PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1293057-C | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1438993-A | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2003-08-27 | — | — | CN | disclosed |