Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | PYGL | P06737 | 9/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1853964 | 0.94 | F10 (0.41) | HRH4HRH3SMYD3F10PYGL | |
| SCHEMBL27547475 | 0.85 | KMT2A (0.58) | HRH4HRH3SMYD3PYGLFLT3 | |
| Hydrochloric Acid SCHEMBL742545 | 0.84 | KMT2A (0.57) | HRH4HRH3SMYD3PYGLFLT3 | |
| SCHEMBL27520223 | 0.82 | SMYD3 (0.45) | HRH4HRH3SMYD3PYGLF7 | |
| Hydrochloric Acid SCHEMBL741656 | 0.81 | SMYD3 (0.44) | HRH4HRH3SMYD3PYGLF7 | |
| SCHEMBL739788 | 0.80 | SMYD3 (0.51) | HRH4HRH3SMYD3PYGLF7 | |
| Hydrochloric Acid SCHEMBL741745 | 0.79 | SMYD3 (0.50) | HRH4HRH3SMYD3PYGLF7 | |
| SCHEMBL743134 | 0.79 | FLT3 (0.47) | HRH4HRH3SMYD3PYGLF7 | |
| SCHEMBL740522 | 0.77 | SMYD3 (0.48) | HRH4HRH3SMYD3PYGLF7 | |
| SCHEMBL740808 | 0.76 | F10 (0.44) | HRH4HRH3SMYD3F10PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |