Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 4/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28287629 | 0.90 | IDH1 (0.39) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| Hydrochloric Acid SCHEMBL28938455 | 0.90 | IDH1 (0.39) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| Hydrochloric Acid SCHEMBL27779692 | 0.90 | IDH1 (0.39) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| Bromide SCHEMBL7178487 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| SCHEMBL10826556 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| SCHEMBL8168378 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| SCHEMBL28333713 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| Fluoride SCHEMBL498860 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA | |
| SCHEMBL21647160 | 0.84 | — | — | |
| SCHEMBL27824504 | 0.84 | IDH1 (0.41) | IDH1CSNK2A2CSNK2BCSNK2A1GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1316314-C | Photographic silver halide emulsion and photographic sensitive silver halide material using sand emulsion | FUJI PHOTO FILM CO LTD (JP) | 2007-05-16 | — | — | CN | disclosed |
| CN-1287218-C | Silver halide photographic optical sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2006-11-29 | — | — | CN | disclosed |
| CN-1836514-A | Novel disinfection and slow-release composition containing BCDMH and its preparation method | GAO XU (CN) | 2006-09-27 | — | — | CN | disclosed |
| CN-1347007-A | Photographic silver halide emulsion and photographic sensitive silver halide material using sand emulsion | FUJI PHOTO FILM CO LTD (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1346073-A | Silver halide photographic optical sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2002-04-24 | — | — | CN | disclosed |
| CN-1028914-C | Silver halide color photographic photo sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1995-06-14 | — | — | CN | disclosed |
| CN-1057343-A | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO LTD (JP) | 1991-12-25 | — | — | CN | disclosed |
| CN-1056584-A | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1991-11-27 | — | — | CN | disclosed |