Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293828 | 0.93 | CYP1A2 (0.58) | CYP1A2GNAO1GNAI3GNAI1HRH3 | |
| Hydrochloric Acid SCHEMBL851007 | 0.91 | GNAO1 (0.58) | CYP1A2GNAO1GNAI3GNAI1HRH3 | |
| Ammonia Solution, Strong SCHEMBL27315646 | 0.91 | CYP1A2 (0.56) | CYP1A2GNAO1GNAI3GNAI1HRH3 | |
| SCHEMBL1368752 | 0.86 | GNAO1 (0.58) | CYP1A2GNAO1GNAI3GNAI1HRH3 | |
| SCHEMBL21284609 | 0.85 | CYP1A2 (0.61) | CYP1A2GNAO1GNAI3GNAI1HRH3 | |
| Hydrochloric Acid SCHEMBL7645440 | 0.84 | GNAO1 (0.61) | CYP1A2GNAO1GNAI3GNAI1ITGB3 | |
| SCHEMBL5494333 | 0.84 | GNAO1 (0.61) | CYP1A2GNAO1GNAI3GNAI1ITGB3 | |
| SCHEMBL7345197 | 0.84 | GNAO1 (0.61) | CYP1A2GNAO1GNAI3GNAI1ITGB3 | |
| SCHEMBL9388856 | 0.84 | GNAO1 (0.61) | CYP1A2GNAO1GNAI3GNAI1ITGB3 | |
| SCHEMBL9388213 | 0.84 | GNAO1 (0.61) | CYP1A2GNAO1GNAI3GNAI1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |