SCHEMBL27520352

SCHEMBL27520352

Nc1cc(-c2ccc(O)nc2)nc(C(=O)O)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMO O15229 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAP4K4 O95819 4/20 0.36
ATR Q13535 1/20 0.36
CTRC Q99895 1/20 0.35
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2465266 0.87 PIK3CD (0.42) KMOTDP1MAP4K4ATRCTRC
SCHEMBL2466879 0.84 KDM4E (0.42)
SCHEMBL2468156 0.82 CTRC (0.51) KMOTDP1ATRCTRCCYP3A4
Ethylene SCHEMBL27521038 0.82 POLB (0.43) TDP1ATRCTRC
SCHEMBL2469483 0.82 MKNK1 (0.46) ATR
SCHEMBL3329998 0.81 CTRC (0.54) TDP1CTRC
SCHEMBL2469999 0.81 MAP2K3 (0.51) TDP1CTRC
SCHEMBL16075484 0.80 MCL1 (0.51)
SCHEMBL16075391 0.80 CTRC (0.39) KMOTDP1ATRCTRCCYP3A4
SCHEMBL2466247 0.80 DHODH (0.49) KMOTDP1ATRCTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1245401-C 6-aryl-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2006-03-15 CN disclosed
CN-1551876-A 6-aryl-4-aminopicolinates and their use as herbicides �ݶ�ũ�����޹�˾ 2004-12-01 CN disclosed