Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7939054 | 0.89 | CYP3A4 (0.33) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL27545994 | 0.79 | NISCH (0.36) | — | |
| Hydrochloric Acid SCHEMBL27521071 | 0.75 | CYP3A4 (0.38) | CYP3A4ACHECYP17A1PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL7935843 | 0.73 | NISCH (0.32) | — | |
| Hydrochloric Acid SCHEMBL7936115 | 0.70 | CYP3A4 (0.35) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL7938864 | 0.70 | CYP3A4 (0.35) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL7926693 | 0.69 | CYP3A4 (0.34) | CYP3A4CYP17A1 | |
| Hydrochloric Acid SCHEMBL4461337 | 0.68 | — | — | |
| SCHEMBL13821776 | 0.67 | CYP3A4 (0.41) | CYP3A4ACHEPTGS1PTGS2CYP11B2 | |
| Hydrochloric Acid SCHEMBL7936959 | 0.66 | CYP3A4 (0.35) | CYP3A4CYP17A1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1274359-A | Mu-oxometallocene complex compound, and olefin polymerization catalyst and polymerization method using same | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |