Formic Acid

Formic Acid

SCHEMBL27523902

O=CO.Oc1ccc(O)c(O)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.52
KDM4E B2RXH2 2/20 0.52
RAB9A P51151 1/20 0.52
LCK P06239 3/20 0.48
NQO2 P16083 1/20 0.48
ALOX5 P09917 2/20 0.48
EGFR P00533 2/20 0.47
MEN1 O00255 1/20 0.47
SRC P12931 1/20 0.47
AKR1B1 P15121 1/20 0.47
NFKB1 P19838 1/20 0.47
CDK2 P24941 1/20 0.47
HSD17B2 P37059 1/20 0.47
PIK3CA P42336 1/20 0.47
NFKB2 Q00653 1/20 0.47
KMT2A Q03164 1/20 0.47
RELA Q04206 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CES2 O00748 1/20 0.46
XDH P47989 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33527 0.86
SCHEMBL4862349 0.86 ALOX5 (0.60) PTGS2LCKNQO2ALOX5CES2
SCHEMBL29829218 0.86
Formaldehyde SCHEMBL732503 0.83 ALOX5 (0.52) PTGS2KDM4ERAB9ALCKNQO2
SCHEMBL31122728 0.83 ALOX5 (0.57) PTGS2LCKNQO2ALOX5CES2
SCHEMBL6676690 0.83 ALOX5 (0.57) PTGS2LCKNQO2ALOX5CES2
Hydrogen Sulfide SCHEMBL11691776 0.83 ALOX5 (0.57) PTGS2LCKNQO2ALOX5CES2
Water SCHEMBL27732048 0.83 ALOX5 (0.57) PTGS2LCKNQO2ALOX5CES2
Phosphine SCHEMBL11514630 0.83 ALOX5 (0.57) PTGS2LCKNQO2ALOX5CES2
Benzene SCHEMBL21834592 0.80 ALOX5 (0.56) PTGS2LCKNQO2ALOX5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106536501-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2017-03-22 CN disclosed
CN-1292884-C Selectively controlling in-mold coating flow including inlet flow control and removable containment flange OMNOVA SOLUTIONS INC (US) 2007-01-03 CN disclosed
CN-1649711-A Selectively controlling in-mold coating flow including inlet flow control and removable containment flange OMNOVA SOLUTIONS INC (US) 2005-08-03 CN disclosed
CN-1642711-A Mold runner for preventing in-mold covering layer from gushing OMNOVA SOLUTIONS INC (US) 2005-07-20 CN disclosed