Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.66 |
| ▸ | RPA1 | P27694 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MARS1 | P56192 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209895 | 0.89 | MEN1 (0.57) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL9207808 | 0.87 | KMT2A (0.78) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL1514409 | 0.85 | KMT2A (1.00) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL27714729 | 0.85 | KMT2A (0.89) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL4493013 | 0.84 | KMT2A (1.00) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL27422557 | 0.84 | KMT2A (0.78) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL9204760 | 0.84 | KMT2A (0.72) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL9204658 | 0.84 | KMT2A (0.72) | KMT2AMEN1ATMPPP1CARPA1 | |
| SCHEMBL9203093 | 0.83 | CHRNA7 (0.72) | KMT2AMEN1ATMPPP1CACHRNA7 | |
| SCHEMBL9203245 | 0.82 | MEN1 (0.70) | KMT2AMEN1ATMPPP1CARPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046506-C | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-17 | — | — | CN | disclosed |