Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.89 |
| ▸ | MEN1 | O00255 | 2/20 | 0.89 |
| ▸ | RPA1 | P27694 | 5/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.64 |
| ▸ | BCL2 | P10415 | 2/20 | 0.64 |
| ▸ | MARS1 | P56192 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514409 | 0.94 | KMT2A (1.00) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL695352 | 0.89 | RPA1 (1.00) | KMT2AMEN1RPA1L3MBTL1PPP1CA | |
| SCHEMBL27694888 | 0.89 | KMT2A (0.71) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL4493013 | 0.87 | KMT2A (1.00) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL9207808 | 0.87 | KMT2A (0.78) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL27422557 | 0.87 | KMT2A (0.78) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL4500796 | 0.85 | L3MBTL1 (1.00) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL27524809 | 0.85 | KMT2A (0.74) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL27694774 | 0.85 | KMT2A (0.69) | KMT2AMEN1RPA1ATML3MBTL1 | |
| SCHEMBL1764890 | 0.85 | KMT2A (0.82) | KMT2AMEN1RPA1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-B | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | INST PHARM & TOXICOLOGY AMMS | 2012-12-26 | — | — | CN | disclosed |
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |