Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727075 | 0.88 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL12509022 | 0.86 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL28801464 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL795938 | 0.83 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6826211 | 0.83 | IDO1 (0.54) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL1145938 | 0.83 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL1145934 | 0.83 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL18095198 | 0.82 | NPC1 (0.47) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL16998546 | 0.79 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL1243268 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292219-B | 1-(cumarone-5-base)-2-(1,2,4-triazol-1-yl) ketoxime heterocycle methyl ether and the application as anticarcinogen thereof | HUNAN UNIVERSITY (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104292219-A | 1-(benzofuran-5-yl)-2-(1,2,4-triazole-1-yl) ketoxime heterocyclic methyl ether and application thereof as anticancer drug | UNIV HUNAN | 2015-01-21 | — | — | CN | claimed |
| CN-104292219-B | 1-(cumarone-5-base)-2-(1,2,4-triazol-1-yl) ketoxime heterocycle methyl ether and the application as anticarcinogen thereof | HUNAN UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104292219-A | 1-(benzofuran-5-yl)-2-(1,2,4-triazole-1-yl) ketoxime heterocyclic methyl ether and application thereof as anticancer drug | UNIV HUNAN | 2015-01-21 | — | — | CN | disclosed |
| CN-100402499-C | 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2008-07-16 | — | — | CN | disclosed |
| CN-1321996-C | Process for producing 2-iminopyrrolidine derivative | SANITATION STUFF R & D MANAGE (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1754880-A | Process for preparing 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-04-05 | — | — | CN | disclosed |
| CN-1243735-C | 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-03-01 | — | — | CN | disclosed |
| CN-1733725-A | Process for preparing 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-02-15 | — | — | CN | disclosed |
| CN-1503784-A | 2-iminopyrrolidine derivatives | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |