SCHEMBL275284

SCHEMBL275284

COc1ccc(-c2nnc(C(Cl)(Cl)Cl)o2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.60
RAB9A P51151 9/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 8/20 0.58
KDM4E B2RXH2 6/20 0.58
HPGD P15428 5/20 0.58
MAPT P10636 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
HSD17B10 Q99714 3/20 0.58
TP53 P04637 2/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
USP2 O75604 1/20 0.57
GSK3B P49841 3/20 0.53
CYP2C19 P33261 2/20 0.51
POLB P06746 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14577297 0.86 NPC1 (0.46) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL13036558 0.85 NPC1 (0.62) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL22117000 0.83 NPC1 (0.63) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL13578724 0.83 NOTUM (0.48) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL13004548 0.82 NPC1 (0.85) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL308805 0.81 NPC1 (0.56) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL13578480 0.80 KDM4E (0.63) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL29085614 0.80 NPC1 (0.55) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL9686677 0.80 MAPK1 (0.61) NPC1RAB9AKMT2AALDH1A1KDM4E
SCHEMBL11219347 0.79 NPC1 (0.43) NPC1RAB9AKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3182204-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-10-20 EP disclosed
EP-2154162-B1 REACTIVE URETHANE COMPOUND HAVING ETHER BOND, CURABLE COMPOSITION AND CURED MATERIAL SHOWA DENKO KK (JP) 2019-07-17 EP disclosed
EP-3182204-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM Corporation (JP) 2017-06-21 EP disclosed
EP-1564591-B1 Polymerizable composition FUJIFILM CORP (JP) 2016-08-03 EP disclosed
EP-2503393-B2 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2016-07-20 EP disclosed
EP-1403710-B1 Polymerizable composition FUJIFILM CORP (JP) 2015-06-10 EP disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8669040-B2 Method of manufacturing relief printing plate and printing plate precursor for laser engraving FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-20050158663-A1 Regenerative plate making and printing process, and plate making and printing apparatus MITSUBISHI HEAVY INDUSTRIES, LTD. (JP) 2005-07-21 US disclosed
US-6877428-B2 Regenerative plate making and printing process, and plate making and printing apparatus MITSUBISHI HEAVY INDUSTRIES, LTD. (JP) 2005-04-12 US disclosed
CN-1529833-A Photosensitive coloring composition, color filter using the same and method for producing the same 昭和电工株式会社 2004-09-15 CN disclosed
US-20040157140-A1 Photosensitive coloring composition, color filter using the composition and method of producing the same SHOWA DENKO K.K. (JP) 2004-08-12 US disclosed
US-20030172828-A1 Regenerative plate making and printing process, and plate making and printing apparatus MITSUBISHI HEAVY INDUSTRIES PRINTING & PACKAGING MACHINERY, LTD. (JP) 2003-09-18 US disclosed
EP-1287986-A1 METHOD AND DEVICE FOR REGENERATIVE PROCESSING AND PRINTING MITSUBISHI CHEMICAL CORPORATION (JP) 2003-03-05 EP disclosed
US-5171655-A Acrylic esters or amides containing pendant maleimide groups; photoresists; short exposure times using scanning laser rays; workability FUJI PHOTO FILM CO., LTD. (JP) 1992-12-15 US disclosed
US-4950582-A CONTAINING POLYURETHANE CONTAINING N-AMINOSULFONYLAMIDO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
US-4877711-A DURABLE PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed