Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178310 | 0.90 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DAOCHRM5 | |
| Hydrochloric Acid SCHEMBL21272596 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM3GRM2DAO | |
| SCHEMBL31616162 | 0.84 | CHRM2 (0.48) | CHRM2CHRM1CHRM3GRM2DAO | |
| SCHEMBL14378216 | 0.83 | CHRM2 (0.50) | CHRM2CHRM1CHRM3GRM2DAO | |
| SCHEMBL2377600 | 0.81 | CHRM2 (0.51) | CHRM2CHRM1CHRM3GRM2DAO | |
| SCHEMBL13463063 | 0.81 | MAOB (0.58) | CHRM2CHRM1CHRM3CETPCARM1 | |
| SCHEMBL7131772 | 0.80 | CHRM2 (0.50) | CHRM2CHRM1CHRM3GRM2DAO | |
| SCHEMBL18015806 | 0.80 | CTSS (0.47) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL2497224 | 0.80 | NPC1 (0.49) | CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL27361117 | 0.80 | CHRM5 (0.49) | CHRM2CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1339432-A | Extracting method for substituted phenyl compounds | ROHM & HAAS (US) | 2002-03-13 | — | — | CN | disclosed |
| CN-1070175-C | Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position | ROHM & HAAS (US) | 2001-08-29 | — | — | CN | disclosed |
| CN-1174189-A | Process for preparing substituted benzene compounds | ROHM & HAAS (US) | 1998-02-25 | — | — | CN | disclosed |