Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL27865282 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1CYP2A6TSHR | |
| Bromobenzene SCHEMBL28023281 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1CYP2A6TSHR | |
| Bromobenzene SCHEMBL27516855 | 0.80 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1CYP2A6TRPA1 | |
| Bromobenzene SCHEMBL27552528 | 0.80 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1CYP2A6TRPA1 | |
| Bromobenzene SCHEMBL27933094 | 0.80 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1CYP2A6TRPA1 | |
| Bromobenzene SCHEMBL28531879 | 0.80 | — | — | |
| Bromobenzene SCHEMBL9418037 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1CYP2A6TSHR | |
| Bromobenzene SCHEMBL22041640 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1CYP2A6TRPA1 | |
| Bromobenzene SCHEMBL27288927 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1CYP2A6MAOA | |
| Bromobenzene SCHEMBL27260817 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1CYP2A6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930159-A | Novel dicationic imidazo [1, 2-a ] pyridine and 5,6,7, 8-tetrahydro-imidazo [1, 2-a ] pyridine compounds as antiprotozoal agents | UNIV NORTH CAROLINA (US) | 2007-03-14 | — | — | CN | claimed |
| CN-103408537-A | 5-substituted dihydrobenzofuran-imidazolium salt compound and preparation method thereof | UNIV YUNNAN | 2013-11-27 | — | — | CN | disclosed |
| CN-101346336-B | 1, 3-di (substituted phenyl) -3-substituted-2-propen-1-one compounds and salts thereof | NISSAN CHEMICAL IND LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-102766135-A | Dihydrofuran indenoane-imidazole salts compound and preparation method thereof | UNIV YUNNAN | 2012-11-07 | — | — | CN | disclosed |
| CN-102757424-A | 2-benzyl-substituted-benzofuran-imidazolium compounds and preparation method thereof | UNIV YUNNAN | 2012-10-31 | — | — | CN | disclosed |
| CN-102473857-A | Organic electroluminescent element | IDEMITSU KOSAN CO | 2012-05-23 | — | — | CN | disclosed |
| CN-102471269-A | Nitrogen-containing heterocyclic derivative and organic electroluminescent element containing same | IDEMITSU KOSAN CO | 2012-05-23 | — | — | CN | disclosed |
| CN-102471340-A | Imidazopyridine derivative and organic electroluminescent element comprising same | IDEMITSU KOSAN CO | 2012-05-23 | — | — | CN | disclosed |
| CN-101340893-B | Intranasal administration of rapid acting insulin | NASTECH PHARM CO | 2012-03-21 | — | — | CN | disclosed |
| CN-102274272-A | Triterpene compositions and methods for use thereof | — | 2011-12-14 | — | — | CN | disclosed |
| CN-1735605-A | Phenylalanine derivative is used for the treatment of or prevent diabetes as depeptidyl peptidase inhibitors | MERCK & CO INC (US) | 2006-02-15 | — | — | CN | disclosed |
| CN-1726044-A | Compositions and methods for enhancing mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity | NASTECH PHARM CO (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| CN-1639145-A | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders | BAYER PHARMACEUTICALS CORP (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1582287-A | Thiophenylthiopyrane dioxides as MMP or TNF-alpha inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-02-16 | — | — | CN | disclosed |
| CN-1496255-A | Inhibition of NF-KB by triterpene compositions | �������о�����չ˽������˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1368970-A | Substituted 1,4-dihydroindeno [1,2-C] pyrazoles as inhibitors of tyrosine kinase | KNOLL GMBH (DE) | 2002-09-11 | — | — | CN | disclosed |
| CN-1314899-A | Retinoid-associated receptor regulators | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-26 | — | — | CN | disclosed |
| CN-1307473-A | Triterpene compositions and methods of their use | RES DEV FOUDATION (US) | 2001-08-08 | — | — | CN | disclosed |
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | disclosed |