⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22387690 | 0.77 | — | — | |
| SCHEMBL18061521 | 0.76 | DRD2 (0.31) | — | |
| SCHEMBL12093059 | 0.76 | DRD2 (0.31) | — | |
| SCHEMBL28332958 | 0.72 | — | — | |
| SCHEMBL23962843 | 0.70 | — | — | |
| SCHEMBL13005258 | 0.70 | — | — | |
| SCHEMBL1881438 | 0.70 | — | — | |
| SCHEMBL3386985 | 0.68 | — | — | |
| SCHEMBL31548447 | 0.68 | — | — | |
| SCHEMBL19570441 | 0.67 | BACE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109611-B1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MAN CO LTD (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-8178552-B2 | 7-Azaindole derivatives and their use in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178552-B2 | 7-Azaindole derivatives and their use in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178552-B2 | 7-Azaindole derivatives and their use in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20100069354-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069354-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069354-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| WO-2008095944-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO. LTD. (JP) | 2008-08-14 | — | — | WO | disclosed |
| EP-0796849-B1 | NOVEL POLYCYCLIC AMINOPYRIDINE COMPOUNDS AS ACETYLCHOLINESTERASE INHIBITORS, PREPARATION PROCESS AND USE THEREOF | MEDICHEM SA (ES) | 2003-11-19 | — | — | EP | disclosed |
| US-5965569-A | TREATING MEMORY DISORDERS SUCH AS SENILE DEMENTIA OR ALZHEIMER'S DISEASE | MEDICHEM, S.A. (ES) | 1999-10-12 | — | — | US | disclosed |
| EP-0796849-A1 | NOVEL POLYCYCLIC AMINOPYRIDINE COMPOUNDS AS ACETYLCHOLINESTERASE INHIBITORS, PREPARATION PROCESS AND USE THEREOF | Camps Garcia, Pelayo (ES) | 1997-09-24 | — | — | EP | disclosed |