Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | BCR | P11274 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 5/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533831 | 0.84 | ABL1 (0.52) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6595300 | 0.78 | ABL1 (0.53) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6594423 | 0.77 | ABL1 (0.62) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6594301 | 0.77 | ABL1 (0.58) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6106058 | 0.75 | ABL1 (0.56) | ABL1BCRPRKCAPRKCDCDK2 | |
| Hydrochloric Acid SCHEMBL6294928 | 0.72 | ABL1 (0.53) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6106065 | 0.72 | ABL1 (0.53) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6103563 | 0.70 | ABL1 (0.53) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL4867623 | 0.70 | ABL1 (0.56) | ABL1BCRPRKCAPRKCDCDK2 | |
| SCHEMBL6254782 | 0.69 | ABL1 (1.00) | ABL1BCRPRKCAPRKCDCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1269813-C | Imidazolo-5-yl-2-anilino-pyrimidines as agents for inhibition of cell proliferation | ASTRAZENECA AB (SE) | 2006-08-16 | — | — | CN | disclosed |