Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.77 |
| ▸ | HTR1D | P28221 | 1/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130495 | 0.87 | HTR1A (1.00) | HTR1AHTR1DSLC6A2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL6599075 | 0.86 | HTR1A (0.98) | HTR1AHTR1DSLC6A2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL27544024 | 0.84 | HTR1A (0.74) | HTR1AHTR1DSLC6A2SLC6A4DRD2 | |
| SCHEMBL6601964 | 0.74 | HTR1A (0.84) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6599055 | 0.72 | HTR1A (0.98) | HTR1AHTR1DSLC6A2SLC6A4DRD2 | |
| SCHEMBL6599069 | 0.71 | HTR1A (1.00) | HTR1AHTR1DDRD2DRD3KMT2A | |
| SCHEMBL3458 | 0.71 | SLC6A2 (0.71) | HTR1AHTR1DSLC6A2SLC6A4 | |
| SCHEMBL3967638 | 0.71 | SLC6A4 (1.00) | HTR1ASLC6A2SLC6A4DRD2KCNH2 | |
| SCHEMBL3359634 | 0.71 | SLC6A4 (1.00) | HTR1ASLC6A2SLC6A4DRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL4413256 | 0.70 | SLC6A4 (0.98) | HTR1ASLC6A2SLC6A4DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265106-A | Thiophene and benzothiophene derivatives and corresponding uses and compositions | VITA INVEST SA (ES) | 2000-08-30 | — | — | CN | claimed |