SCHEMBL27536645

SCHEMBL27536645

O=C(O)c1ccoc1.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142183 0.97
Hydrochloric Acid SCHEMBL4253131 0.95
Formaldehyde SCHEMBL27533174 0.93 MAPT (0.47)
Methylamine SCHEMBL27945126 0.91 TRPA1 (0.47)
Acetone SCHEMBL28506095 0.91 TRPA1 (0.47)
Trimethylammonium SCHEMBL27360406 0.89 TRPA1 (0.46)
Ethylene Glycol SCHEMBL28192812 0.89 TRPA1 (0.46)
Biphenyl SCHEMBL27717152 0.87 MAPT (0.51)
SCHEMBL6612952 0.82 EGFR (0.53)
Ethanesulfonic Acid Amide SCHEMBL7621819 0.80 TRPA1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1095379-A Condensed heterocyclic derivates and weedicide KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-11-23 CN disclosed
CN-86102923-A The method for preparing antibiotic derivatives 1986-11-12 CN disclosed