Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516484 | 0.85 | PDE10A (0.46) | PDE10AMAP4K4 | |
| SCHEMBL2411355 | 0.83 | CDK1 (0.39) | CDK1CDK2PDE10AMAP4K4HRH3 | |
| SCHEMBL27565772 | 0.82 | MAP4K4 (0.43) | APAF1PDE10AMAP4K4HRH4HTR3A | |
| SCHEMBL27516810 | 0.81 | HRH4 (0.44) | PDE10AMAP4K4HRH3HRH4HTR3A | |
| SCHEMBL27538307 | 0.77 | TACR1 (0.34) | APAF1PDE10A | |
| SCHEMBL27517764 | 0.77 | MCHR1 (0.46) | MAP4K4 | |
| SCHEMBL27516160 | 0.76 | SCN9A (0.38) | APAF1MAP4K4 | |
| SCHEMBL27515451 | 0.72 | PDE10A (0.38) | CDK1CDK2PDE10A | |
| SCHEMBL27570923 | 0.69 | APAF1 (0.32) | APAF1 | |
| SCHEMBL2413196 | 0.69 | PDE10A (0.39) | CDK1CDK2PDE10AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250192-C | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2006-04-12 | — | — | CN | claimed |
| CN-1425365-A | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2003-06-25 | — | — | CN | claimed |
| CN-1250192-C | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2006-04-12 | — | — | CN | disclosed |
| CN-1425365-A | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2003-06-25 | — | — | CN | disclosed |