Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.59 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532069 | 0.91 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL27532343 | 0.89 | PTGS2 (0.60) | PTGS2BCL2MCL1 | |
| SCHEMBL27532332 | 0.89 | PTGS2 (0.53) | PTGS2MCL1 | |
| SCHEMBL27554513 | 0.87 | PTGS2 (0.57) | PTGS2 | |
| SCHEMBL27554532 | 0.87 | PTGS2 (0.57) | PTGS2BCL2MCL1 | |
| SCHEMBL6169948 | 0.86 | PTGS2 (0.73) | PTGS2 | |
| SCHEMBL27540633 | 0.84 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL27554745 | 0.84 | PTGS2 (0.49) | PTGS2BCL2MCL1 | |
| SCHEMBL27531805 | 0.83 | PTGS2 (0.61) | PTGS2MCL1 | |
| SCHEMBL27531749 | 0.83 | PTGS2 (0.52) | PTGS2BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | claimed |
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | disclosed |