Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 9/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789815 | 0.79 | PPARG (0.74) | KCNK3KCNK9PPARG | |
| SCHEMBL231897 | 0.77 | KDR (0.78) | GRM4KCNK3KCNK9KDRHDAC6 | |
| SCHEMBL993581 | 0.77 | KDR (0.64) | GRM4KCNK3KCNK9KDRHDAC6 | |
| SCHEMBL29184186 | 0.76 | KDR (0.76) | GRM4KCNK3KCNK9KDRHDAC6 | |
| SCHEMBL10322846 | 0.75 | PLAU (0.61) | KCNK3KCNK9PPARG | |
| SCHEMBL30693673 | 0.73 | NPC1 (0.63) | GRM4KCNK3KCNK9KDRAURKB | |
| SCHEMBL4323035 | 0.73 | NPC1 (0.63) | GRM4KCNK3KCNK9KDRAURKB | |
| SCHEMBL10860493 | 0.73 | MEN1 (0.59) | GRM4KCNK3KCNK9 | |
| SCHEMBL3645013 | 0.73 | MEN1 (0.74) | HDAC6 | |
| SCHEMBL6278943 | 0.72 | GRM4 (1.00) | GRM4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285578-C | Substituted benzoic acid amides and their use in inhibiting angiogenesis | SCHERING AG (DE) | 2006-11-22 | — | — | CN | disclosed |
| CN-1426396-A | Substituted benzoic acid amides and use for inhibition of angiogenesis thereof | SCHERING AG (DE) | 2003-06-25 | — | — | CN | disclosed |