Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.67 |
| ▸ | RARB | P10826 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825079 | 0.94 | RARB (0.74) | TP53TSHRPLA2G4BRARBALDH1A1 | |
| SCHEMBL7825121 | 0.94 | RARB (0.74) | TP53TSHRPLA2G4BRARBALDH1A1 | |
| SCHEMBL8208816 | 0.94 | TP53 (0.78) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8208895 | 0.94 | TP53 (0.78) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7166454 | 0.90 | RARB (0.80) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7171418 | 0.90 | RARB (0.80) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7166474 | 0.90 | RARB (0.80) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2889825 | 0.88 | TP53 (0.77) | TP53TSHRPLA2G4BRARBALDH1A1 | |
| SCHEMBL7171032 | 0.87 | RARB (0.84) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7171028 | 0.87 | RARB (0.84) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1314906-A | Salts of paroxetine | SMITHKLINE BEECHAM PLC (GB) | 2001-09-26 | — | — | CN | disclosed |