Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.65 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825079 | 1.00 | RARB (0.74) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| Arachidonic Acid SCHEMBL27543066 | 0.94 | TP53 (0.68) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7171028 | 0.94 | RARB (0.84) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7171026 | 0.94 | RARB (0.84) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7171032 | 0.94 | RARB (0.84) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7166454 | 0.91 | RARB (0.80) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7171418 | 0.91 | RARB (0.80) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7166474 | 0.91 | RARB (0.80) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8208816 | 0.87 | TP53 (0.78) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8208895 | 0.87 | TP53 (0.78) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |